Nanocatalytic system releases overloaded zinc ions and ROS to induce Znproptosis and interrupt cell cycle through inhibiting Akt/mTOR pathway
Year: 2025
Type: article
Abstract: Hence, the research reveals a detailed Znproptosis mechanism in nanocatalytic system. Through regulating FDX2/LIAS pathway, Znproptosis could improve the death rate of mitochondria by decreasing the production of Fe-S protein, contributing to advancements in the field of antitumor therapy.
Source: Theranostics
DOI: 10.7150/thno.107025
Authors: Zi-Yue Xi, Chuan-Yong Fan, Ying-Ying Jiang, Xin-Ran Xi, Gan-Yu Nie, Shuang Zhu, Jun-Jie Zhang, Lu Xu
Institution: Shenyang Pharmaceutical University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,671
OpenAlex ID: W4409300809