Work

An innovative magnetic l-lysine-dialdehyde nanocellulose for sonochemical heterogeneous catalysis in the green synthesis of ultrapure tri-substituted imidazoles

Year: 2025

Type: article

Abstract: In this contribution, we report the first ultrasound-assisted synthesis of magnetically modified l -lysine dialdehyde nanocellulose and its use in an efficient ecological catalytic application. The structure of designed nanomaterial [Lys-g-DANC)@Fe 3 O 4 ] was successfully elucidated using various structural, morphological, thermal, optical and magnetic techniques. Next, it was utilized as a heterogeneous nano-catalyst in an ecofriendly and effective process following one-pot multicomponent synthesis of tri-substituted imidazoles . The catalytic procedure afforded seven imidazole byproducts in outstanding yields (83.45–97.13 %) using ultrasound irradiation , 0.03 g of [Lys-g-DANC)@Fe 3 O 4 ], 10 mL of ethanol at 45 °C and in limited time ranges (1.5–3 h). The structures of obtained imidazole derivatives were elucidated using FTIR and NMR spectroscopic techniques. This work proves the efficiency of magnetically l -lysine nanocellulose in catalytic procedures compared to classical heating protocols including increased yields, limited reaction time ranges, simple catalyst separation and its effective recyclability.

Source: International Journal of Biological Macromolecules

DOI: 10.1016/j.ijbiomac.2025.142842

Authors: Soumaya Agren, Rahma Mehdaoui, Marwa Chaabene, Jamal El Haskouri, Emmanuel Beyou, Mohamed Hassen V. Baouab