Work

The Potential of Ruthenium(II) Tris‐Bidentate Complexes as Multifunctional Photo‐Initiators

Year: 2025

Type: article

Abstract: An optically active antibacterial ruthenium(II) phenanthroline complex (tris(3,4,7,8‐tetramethyl‐1,10‐phenanthroline) ruthenium(II) dichloride), is investigated for its potential as a multifunctional photo‐initiator. Antibacterial and cytotoxic studies indicated that the complex is biologically active, and viable below <0.5 mm. The complex is shown to photo‐polymerize gelatin using visible light in a similar manner to tris(2,2′‐bipyridyl)ruthenium(II) dichloride and is demonstrated to retain antibacterial activity post‐fabrication of a gelatin hydrogel. Incorporation of the photo‐initiator into the interstitial fluid of a hybrid gelatin granular scaffold generated a multifunctional scaffold that retained cell viability and exhibited injectable properties.

Source: Macromolecular Materials and Engineering

DOI: 10.1002/mame.202400458