Using vaporized hydrogen peroxide for anhydrous disinfection of gastrointestinal endoscopes
Year: 2025
Type: article
Abstract: BACKGROUND Current disinfection methods for gastrointestinal endoscopes consume a significant amount of water resources and produce a large volume of waste. AIM To achieve the objectives of efficiency, speed, and cost-effectiveness, this study utilized vaporized hydrogen peroxide (VHP) generated from sodium percarbonate granules to conduct an anhydrous disinfection test on gastrointestinal endoscopes. METHODS The experimental device rapidly converts sodium percarbonate granules into VHP, and performs disinfection experiments on gastrointestinal endoscope models, disposable endoscopes, and various types of reusable gastrointestinal endoscopes. Variables such as the intraluminal flow rate (FR), relative humidity (RH), exposure dosage, and organic burden are used to explore the factors influencing the disinfection of long and narrow lumens with VHP. RESULTS The device generates a certain concentration of VHP that can achieve high-level disinfection of endoscope models within 30 minutes. RH, exposure dosage, and organic burden significantly affect the disinfection efficacy of VHP, whereas the intraluminal FR does not significantly impact disinfection efficacy. All ten artificially contaminated disposable endoscopes achieved satisfactory disinfection results. Furthermore, when this device was used to treat various types of reusable endoscopes, the disinfection and sterilization effects were not significantly different from those of automatic endoscope disinfection machines (using peracetic acid disinfectant solution) (P > 0.05), and the economic cost of disinfectant required per endoscope was lower (1.5 China Yuan), with a shorter disinfection time (30 minutes). CONCLUSION The methods and results of this study provide a basis for further research on the use of VHP for the disinfection of gastrointestinal endoscopes, as well as for the development of anhydrous disinfection technology for gastrointestinal endoscopes.
Authors: Can Zhao, Li-Hong Qi, Long-Song Li, Ying-Ying Wang, Ting Liang, Ning-Li Chai
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4409309769