Work

New drugs are not enough: addressing social determinants as a critical component of drug-resistant TB care

Year: 2025

Type: article

Abstract: The global fight against drug-resistant TB (DR-TB) is hindered by an underappreciation of the importance of the social determinants of TB. Although shorter, all-oral regimens have improved treatment options, high rates of non-adherence persist due to stigma, financial hardship and other healthcare access barriers. Lessons from HIV highlight the importance of addressing structural and psychosocial factors in treatment management. Consideration of an ecosocial framework integrating biological, social and environmental perspectives is critical for effective DR-TB interventions. A paradigm shift toward patient-centered care and social support strategies is urgently needed to improve treatment outcomes and advance global efforts to eradicate DR-TB.

Source: IJTLD OPEN

DOI: 10.5588/ijtldopen.25.0075

Authors: D. Giovenco, N.S. Shah, K. Ansorge, D. Operario, N.R. Gandhi

Institution: Emory University

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Reduced inequalities

Open Access status: diamond

Funder: National Institute of Allergy and Infectious Diseases