Safety of bioinductive bovine collagen implants for arthroscopic rotator cuff repair
Year: 2025
Type: article
Abstract: Background: Bioinductive reconstituted type I bovine collagen implants for augmenting arthroscopic rotator cuff repair (ARCR) may improve the healing rate and thickness of repaired tendons. However, there are concerns regarding the inflammatory responses and foreign body reactions associated with the use of foreign substances. This study aimed to evaluate the safety of type I bovine collagen bioinductive implants in ARCR. Methods: < .05. Results: CRP levels and WBC counts normalized within 2 weeks postoperatively in both the R and N-R groups, with no significant differences between the groups at any time point. Effusions in the glenohumeral joints and subacromial bursa were present in both groups and were not significantly different between the R and N-R groups at 1 and 6-8 weeks postoperatively. No reoperations due to infection or inflammatory responses were observed within 6 months postoperatively in either group. Conclusion: The use of reconstituted type I bovine collagen bioinductive implants in ARCR did not significantly affect postoperative inflammatory responses or increase the risk of effusion. The absence of reoperations due to clinical infections or foreign body reactions further supports the safety of the implants.
Source: JSES International
Authors: Hideki Kinjo, Naoki Suenaga, Naomi Oizumi, Kotaro Nishida
Institution: University of the Ryukyus
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,250
OpenAlex ID: W4409314067