Work

Exploring the role of urinary brain-derived neurotrophic factor in diagnosis and follow-up of overactive bladder in women: A prospective analytical study in a tertiary care center experience

Year: 2025

Type: article

Abstract: Objective: Overactive bladder (OAB) is a common clinical manifestation of voiding dysfunction. It is a symptom-based condition. A new, accurate, objective, and noninvasive test to diagnose OAB and assess therapeutic outcomes is lacking. The study aimed to assess the use of the urinary biomarker brain-derived neurotrophic factor (BDNF), as a non-invasive diagnostic and follow-up tool. Methods: =48). Results: <0.001). Conclusion: BDNF can be used to assess the presence of OAB and follow up the course of OAB as a supplementary tool to clinical assessment and urodynamics.

Source: Asian journal of urology

DOI: 10.1016/j.ajur.2024.12.006

Authors: Hussein Aly Hussein, Mostafa Sheba, Aly Ahmed Shams El Din, Mohamed Tawfik, Samer Morsy

Institutions: Cairo University, Cairo University hospitals

Language: English

Topic: Urinary Bladder and Prostate Research

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Tongji University