Work

Pemphigus Vulgaris Post-typhoid Fever: A Case Report and Therapeutic Perspectives

Year: 2025

Type: article

Abstract: Pemphigus vulgaris (PV) is a rare autoimmune disorder causing blisters affecting the skin and mucous membranes. This case study discusses the case of a 52-year-old male who developed PV following typhoid fever, presenting with painful fluid-filled lesions that progressed to erosions. The diagnosis was confirmed through a skin biopsy and immunofluorescence. Treatment with corticosteroids, intravenous antibiotics, and supportive care led to gradual improvement. This case underscores the importance of early diagnosis and highlights rituximab’s potential in reducing steroid dependency and improving outcomes. Timely intervention and evolving strategies are essential to enhance management and minimize complications of long-term steroid use.

Source: D Y Patil Journal of Health Sciences

DOI: 10.4103/dypj.dypj_6_25

Authors: Princy Domnic Dsouza, Sai Phalguna Prakash Chitralu, Sanatkumar Bharamu Nyamagoud

Institution: KLE Academy of Higher Education and Research

Language: English

Topic: Autoimmune Bullous Skin Diseases

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4409317601

FWCI:

Cites: 9

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Related to: 10