Year: 2025
Type: article
Abstract: Gram-negative Bacteria Most antibiotics are ineffective against Gram-negative bacteria due to the presence of the outer membrane (OM). In article number 2411923, Jianzhong Shen, Kui Zhu, and co-workers screened natural xanthone skeletons with the potential to penetrate the OM after amine modification. These optimized compounds cross the OM via a self-promoted pathway, facilitating the discovery of novel antibacterial agents.
Source: Advanced Science
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $6,730
OpenAlex ID: W4409323584