Work

Hereditary diseases and tumors in children

Year: 2025

Type: article

Abstract: In recent years, our ability to use genome-wide analyses, including whole-genome and whole-exome sequencing, to determine the genetic basis of pediatric tumors has expanded significantly. In particular, exome sequencing has contributed the evidence that approximately 10 % of children and adolescents with tumors have genetic variant mutations associated with cancer susceptibility.In this review, we present a list of some genetic variations predisposing children to solid tumors.

Source: Podderživaûŝaâ terapiâ v onkologii.

DOI: 10.17650/3034-2473-2025-2-1-21-29

Authors: S. A. Kulyova, A. A. Ryazankina, M. М. Vasileva

Institutions: Institute of Oncology NN Petrov, Ministry of Health of the Russian Federation, Saint Petersburg State Pediatric Medical University, North-Western State Medical University named after I.I. Mechnikov

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4409343524

FWCI:

Cites: 60

Cited by:

Related to: 10