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Cartilage targeting cationic peptide carriers display deep cartilage penetration and retention in a rabbit model of post-traumatic osteoarthritis

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Year: 2025
Type: article
Source: Osteoarthritis and Cartilage
DOI: 10.1016/j.joca.2025.04.001
Authors: Timothy L. Boyer, Olivia Chao, Bill Hakim, Luke Childress, Quentin A. Meslier, Suhasini M. Iyengar, Mary Jo Ondrechen, Ryan M. Porter, Ambika G. Bajpayee
Institutions: Northeastern University, University of Arkansas Medical Center, University of Arkansas for Medical Sciences
Language: English

Topic: Osteoarthritis Treatment and Mechanisms
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Northeastern University, National Institute of General Medical Sciences, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Biomedical Imaging and Bioengineering
Awards: Systems Pharmacology and Toxicology Training Program, G1928536634, G585391699, Anti-catabolic drug anchored cationic exosomes for cartilage targeting and repair, G7283991726, G8095157482, Center for Musculoskeletal Disease Research (CMDR), Intra-cartilage depot delivery of electrically-charged IL-1RA for targeting osteoarthritis-associated inflammation and catabolism in multiple joint tissues
OpenAlex ID: W4409360655
FWCI: 10.95
Cites: 51
Cited by: 15
Related to: 10
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