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Idiopathic Granulomatous Appendicitis: A Case Report and Review of the Literature

Year: 2025

Type: article

Abstract: Idiopathic granulomatous appendicitis (IGA) is a rare condition that clinically presents similar to acute appendicitis, with symptoms such as abdominal pain, fever, and anorexia. We report a case of a 30-year-old postpartum female who presented with symptoms of acute appendicitis. Imaging revealed a thickened appendix, and laparoscopic appendectomy was performed. Intraoperative findings led to conversion to laparotomy with ileocolic resection. Histopathology confirmed granulomatous appendicitis with focal suppuration and no evidence of Crohn's disease or infection. IGA is diagnosed by excluding other infectious or non-infectious causes, and appendectomy is the treatment of choice, with a favorable prognosis. The condition requires careful pathological evaluation to avoid unnecessary extensive surgery.

Source: Cureus

DOI: 10.7759/cureus.82081

Authors: Abanoub Awad, Isaac Theerman, Jason Beckermann

Institution: Mayo Clinic Health System

Language: English

Topic: Appendicitis Diagnosis and Management

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409365637