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A Rare Case of Primary Hyperaldosteronism Resulting in Severe Hypokalemia

Year: 2025

Type: article

Abstract: Hyperaldosteronism often clinically manifests as hypertension with mild to moderate hypokalemia. However, in rare cases, it can also present primarily with severe hypokalemia. In this case report, we will be discussing our patient, a 43-year-old woman who presented with abdominal cramps and vomiting, along with severe muscle cramps resulting in an inability to walk. She was found to have an undetectable level of serum potassium and prolonged QT interval on her ECG. After aggressive electrolyte correction and further imaging and endocrinology studies, she was diagnosed to have primary hyperaldosteronism. She was appropriately referred for urgent outpatient adrenalectomy, which turned out to be curative. Our case highlights the importance of timely diagnosis, interventions, and multidisciplinary care for patients with primary hyperaldosteronism.

Source: Cureus

DOI: 10.7759/cureus.82069

Authors: Saad Sameer, Aya J Qassim, Ali Aqel, Yousef H Al-Asa'd, Shaefiq Babu Thappy

Institutions: Hamad General Hospital, Hamad Medical Corporation

Language: English

Topic: Hormonal Regulation and Hypertension

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409368137