Work

Arynes in green solvent: employing o -silylaryl triflates with propylene carbonate

Year: 2025

Type: article

Abstract: -silylaryl triflate precursors are shown to engage with a range of arynophiles in propylene carbonate solvent. Possessing similar physicochemical properties to acetonitrile, propylene carbonate is found to be an effective direct solvent replacement, affording similar yields and promoting increased reaction rates. This is the first time that arynes have been used in conjunction with green and sustainable cyclic carbonate solvents.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/d5ob00273g

Authors: Heike Friedrich, Khushal Siddiq, Najwa Arafah, Roland Kulanda, Laura G. Aguilar-Sanchez, Christopher R. Jones

Institution: Queen Mary University of London

Language: English

Topic: Cyclization and Aryne Chemistry

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: hybrid

Funders: Royal Society of Chemistry, Deutscher Akademischer Austauschdienst, Instituto Politécnico Nacional