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Chiral iron porphyrin (+)-D 4 -(por)FeCl catalyzes highly enantioselective cyclopropanation of alkenes using in situ generated diazoacetonitrile with up to 35 000 product turnover

Year: 2025

Type: article

Abstract: Chiral iron porphyrins catalyze the asymmetric cyclopropanation of a variety of aryl olefins via a reactive iron-cyanocarbene intermediate with high enantioselectivity and product turnover.

Source: Chemical Science

DOI: 10.1039/d5sc00461f

Authors: Hao-Chong Tan, Ka-Pan Shing, Hua-Hua Wang, Yungen Liu, Chi-Ming Che

Institutions: Southern University of Science and Technology, State Key Laboratory of Synthetic Chemistry, University of Hong Kong

Language: English

Topic: Cyclopropane Reaction Mechanisms

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Innovation and Technology Commission, Southern University of Science and Technology

OpenAlex ID: W4409371119

FWCI: 1.788

Cites: 88

Cited by: 6

Related to: 10