Work

Metabolomics and Antioxidant Activity of Valonea from Quercus variabilis Produced in Different Geographical Regions in China

Year: 2025

Type: article

Abstract: The genus Quercus is widely distributed globally and serves as a potential source of phenolic compounds, which are renowned for their potent biological activities. The primary objective of this study was to determine the concentrations of metabolite components and evaluate the relative antioxidant activities of valonea (acorn cups) from Quercus variabilis (Q. variabilis) of different geographic origins using a UPLC-ESI-MS/MS-based metabolomics approach. A total of 791 metabolite components were identified, with significant variations in their concentrations observed among samples from different geographic locations. Among these, 1-O-galloyl-β-D-glucose was identified as a key active compound. The biosynthesis of galloyl sugars, galactose metabolism, and pathways for starch and sucrose metabolism represent the three pathways that correspond to the differential metabolites, encompassing 23, 11, and 7 metabolites, respectively. The variations in the antioxidant effectiveness of valonea could mainly be linked to the synthesis of galloyl sugars. These findings improve our knowledge of the composition of valonea and offer valuable resources for its extensive utilization and focused development.

Source: International Journal of Molecular Sciences

DOI: 10.3390/ijms26083599

Authors: Zhenkai Tong, Hao Zhou, Zhiwen Qi, Jianxin Jiang, Wenjun Li, Chengzhang Wang

Institutions: Beijing Forestry University, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry

Language: English

Topic: Phytochemistry and Biological Activities

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,499

Funder: Government of Jiangsu Province