Chandipura virus in India: A comprehensive epidemiological review
Year: 2025
Type: article
Abstract: The Chandipura virus (CHPV) is an emerging arbovirus in India, transmitted primarily by sandflies and associated with outbreaks of acute encephalitis in children. First identified in 1965 in Maharashtra, CHPV has since been linked to Acute Encephalitis Syndrome (AES) in several states, including Maharashtra, Gujarat, Telangana, and Madhya Pradesh. The virus predominantly affects children under 15 years, particularly in rural areas with poor housing conditions, and is most prevalent during the monsoon season when sandfly activities are high. Its clinical presentation includes a rapid-onset febrile illness progressing to encephalitis, often with a high case fatality rate. Diagnostic challenges arise due to similarities with other arboviral infections, complicating outbreak management. Current public health interventions emphasize vector control, environmental sanitation, and community awareness, though the lack of specific antiviral treatment and vaccines remains a significant barrier. This review highlights the need for improved surveillance, diagnostic tools, and vaccine development to mitigate the potential public health impact of CHPV in India. A One Health approach, integrating human, animal, and environmental health, is crucial for the effective management and prevention of CHPV outbreaks.
Source: Journal of Vector Borne Diseases
Authors: Neeraj Pawar, Aswani Kumar Seth
Institution: All India Institute of Medical Sciences
Language: English
Topic: Viral Infections and Vectors
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409374394