Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: Neurosyphilis is a rare but serious complication of syphilis, especially in HIV-co-infected patients. This study examines the clinical and evolutionary characteristics of neurosyphilis in this population. Materials and Methods: A retrospective study conducted in the infectious diseases department from January 2012 to August 2024, including all HIV-positive patients who developed neurosyphilis. Results: Among 15 patients, the average age was 44.14 years, with a male predominance (sex ratio=2). Behavioral disturbances were the most frequent clinical manifestations (33.33%). The syphilitic serology in the cerebrospinal fluid (CSF) was positive in 26% of cases. Conclusion: Neurosyphilis in HIV-positive patients remains a diagnostic challenge. Early management with penicillin G treatment allows for favorable outcomes in most cases.
Authors: Elfargani R, Ait Driss W, Idalene M, Tassi N
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409376266