Work

Transdermal delivery of timolol maleate using hydrogel microneedles for the treatment of infantile haemangiomas

Year: 2025

Type: article

Abstract: studies on nude mice demonstrated that BSAMA-TIM-MNs inhibited the growth of haemangioma xenografts. Our TIM-delivering MNs exhibited high therapeutic efficacy, minimal cytotoxicity, and reduced dosing frequency. In conclusion, BSAMA-TIM MNs provide a promising strategy for treating IH.

Source: Materials Today Bio

DOI: 10.1016/j.mtbio.2025.101752

Authors: Xiaokun Lin, Tongshuai Kuang, Lei Wang, Wei Cai, Linxing Yang, Changrong Guo, Xinyang Pan, Yuanhao Wang, Qiang Gao, Kaihui Nan, Lingli Li

Institutions: Wenzhou Medical University, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou Institute, University of Chinese Academy of Sciences

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,400

Funders: Wenzhou Medical University, University of Chinese Academy of Sciences, Natural Science Foundation of Zhejiang Province

Awards: G1348831495, G3379105139, 双动力脂质体-水凝胶复合载药体系的构建及其在TON 模型中对RGC 的保护作用

OpenAlex ID: W4409392609

FWCI: 4.047

Cites: 77

Cited by: 10

Related to: 10