Work

Proteome‐Wide Data Guides the Discovery of Lysine‐Targeting Covalent Inhibitors Using DNA‐Encoded Chemical Libraries

Year: 2025

Type: article

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.202505581

Authors: Xinyuan Wu, Shunyao Li, Ting Liang, Qing Yu, Yiwei Zhang, Jiaxiang Liu, Kaige Li, Zijian Liu, Mengqing Cui, Yongchao Zhao, Xin Han, Rui Jin, Minjia Tan, Xiao‐Hua Chen, Yujun Zhao, Mingyue Zheng, Yi Sun, Lu Zhou, Xiaojie Lu

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Fudan University, Second Affiliated Hospital of Zhejiang University, Zhejiang University, Zhejiang Cancer Hospital, Nanjing University of Chinese Medicine, First Affiliated Hospital Zhejiang University

Language: English

Topic: Click Chemistry and Applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China

Awards: G270790173, G2763932694, G3005146028, G3215655507, G3999105043, G5336272186, G6592492841, G8652919544

OpenAlex ID: W4409403580

FWCI: 5.633

Cites: 61

Cited by: 19

Related to: 10