[Effect of CMTM6 on PD-L1 in Helicobacter pylori infected gastric epithelial cells].
Year: 2025
Type: other
Abstract: OBJECTIVE: infected gastric epithelial cells by microarray analysis. METHODS: gene knockout and wild-type GES-1 cells co-cultured with Hp for 48 hours, and the signal pathway of differentially expressed genes enrichment was analyzed by Kyoto Encyclopedia of Genes and Genomes (KEGG) database. RESULTS: gene knockout, adrenoceptor alpha 1B (ADRA1B), cholinergic receptor muscarinic 1 (M1), CHRM1, platelet activating factor receptor (PTAFR) gene expression was significantly up-regulated. CONCLUSION: gene knockout may affect biological behaviors such as protein ubiquitination and cell surface receptor expression.
Source: PubMed
Authors: Wei Fu, Jing Ning, Weiwei Fu, Jing Zhang, Shigang Ding
Institution: Peking University Third Hospital
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4409410509