Work

Myopia progression in children with Stickler syndrome: a longitudinal cohort study

Year: 2025

Type: article

Abstract: Studies of myopia progression in congenital myopia, as seen in genetically confirmed Stickler syndrome, are scarce. Stickler syndrome represents the most common cause of rhegmatogenous retinal detachment in children. The purpose of this retrospective study was to determine the rate of myopia progression in a cohort of 40 children (75 eyes) with type 1 Stickler syndrome (COL2A1 mutation) and 5 children (10 eyes) with type 2 Stickler syndrome (COL11A1 mutation). In this cohort, the median rate of progression was -0.08 D per year for those with type 1 Stickler syndrome and -0.12 D per year for those with type 2 Stickler syndrome, indicating minimal myopia progression in these children.

Source: Journal of American Association for Pediatric Ophthalmology and Strabismus

DOI: 10.1016/j.jaapos.2025.104206

Authors: Nisha Nixon, Kelly H. Cheng, Allan Richards, Howard Martin, Martin P. Snead, Brinda Muthusamy

Institutions: Cambridge University Hospitals NHS Foundation Trust, University of Cambridge

Language: English

Topic: Ophthalmology and Visual Impairment Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,330