Work

Machine Learning and Structural Dynamics-Based Approach to Reveal Molecular Mechanism of PTEN Missense Mutations Shared by Cancer and Autism Spectrum Disorder

Year: 2025

Type: article

Source: Journal of Chemical Information and Modeling

DOI: 10.1021/acs.jcim.5c00134

Authors: Miao Yang, Jingran Wang, Ziyun Zhou, Wentian Li, Gennady Verkhivker, Fei Xiao, Guang Hu

Institutions: Soochow University, Chapman University

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Priority Academic Program Development of Jiangsu Higher Education Institutions, National Institutes of Health

Awards: G2624156301, G3163042092, Probing real-time conformational dynamics and allosteric cooperativity of the HIV-1 envelope glycoprotein during virus entry, G5732843278

OpenAlex ID: W4409425523

FWCI: 0.522

Cites: 52

Cited by: 2

Related to: 10