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Cobaltabis(dicarbollide) [ o -COSAN] − loaded apoferritin: an innovative high-capacity boron delivery system to target tumour cells for BNCT applications

Year: 2025

Type: article

Abstract: showed significant cytotoxic effects following neutron irradiation, highlighting the potential of this system in BNCT. These findings underscore the versatility of apoferritin as a multifunctional nanocarrier for targeted cancer therapy, combining high boron payloads with selective tumour cell uptake.

Source: Nanoscale

DOI: 10.1039/d5nr00362h

Authors: D. Alberti, J. N. Piña Marcos, S. Rakhshan, N. Protti, S. Altieri, M. Nuez-Martínez, F. Teixidor, C. Viñas, S. Geninatti Crich

Institutions: University of Turin, Istituto Nazionale di Fisica Nucleare, University of Pavia, Istituto Nazionale di Fisica Nucleare, Sezione di Pavia, Institut de Ciència de Materials de Barcelona

Language: English

Topic: Boron Compounds in Chemistry

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Associazione Italiana per la Ricerca sul Cancro

Award: G1067259717

OpenAlex ID: W4409428215

FWCI: 4.263

Cites: 55

Cited by: 8

Related to: 10