The impact of arterial cannulation strategy on carotid perfusion during cardiopulmonary bypass: A computational fluid dynamics analysis from the perspective of vascular anatomy
Year: 2025
Type: article
Abstract: Introduction: Cardiopulmonary bypass (CPB) is utilized during cardiovascular surgery to maintain organ oxygen supply and blood perfusion instead of cardiopulmonary function. Three primary methods of artery cannulation used for CPB include ascending aortic cannulation (AscAoC), right axillary artery cannulation (rAxAC), and femoral artery cannulation (FAC). Methods: In this study, computational fluid dynamics simulation technology was employed to analyze aorta and main branches of 62 patients undergoing CPB with different arterial cannulation schemes, observing carotid artery (CarA) perfusion and characteristics. Conclusions: Results indicate that the total perfusion of bilateral CarAs using the three cannulation methods was sufficient when there was no significant variation in arterial morphology. Without considering the peripheral resistance and the body’s autoregulatory function, the right CarA was less perfused than the left CarA under AscAoC and rAxAC, leading to perfusion imbalance. Especially heteroplastic patients with rAxAC may be at risk of the right CarA hypoperfusion during CPB. FAC provides balanced and adequate perfusion of both hemispheres without stenosis or dissection of the aorta.
Source: Perfusion
Authors: Shengxun Lu, Yachuang Xing, Jie Liu, Jinghua Li, Shengkai Zhou, Guiqing Liu, Feng Wang, Junhui Luo
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4409433131