Work

Identification of a neural tube defect in embryoscopic study for pregnancy loss

Year: 2024

Type: article

Abstract: Pregnancy loss has a significant emotional impact on couples, with many seeking explanations for recurrent miscarriages. Despite investigations, many cases remain unexplained. We report a case of a 39-year-old woman with recurrent pregnancy loss and a non-viable twin gestation at 7 weeks + 6 days, in which hystero-embryoscopy was performed. A neural tube defect was observed, and cytogenetic analysis disclosed trisomy 18 and 21. This technique provides direct visualization of embryo morphology, allows for cytogenetic sampling of embryo and trophoblastic tissue, and treats retained products of conception. It enhances diagnosis and reduces risks, benefiting couples facing recurrent pregnancy loss.

Source: Acta Obstétrica e Ginecológica Portuguesa

DOI: 10.69729/aogp.v18i4a09

Authors: ULS do Tâmega e Sousa, Fabiana Castro, Ana Portela Carvalho, ULS do Tâmega e Sousa, Cristina Oliveira, ULS do Tâmega e Sousa

Institution: Unidade Hospitalar de Amarante

Language: English

Topic: Prenatal Screening and Diagnostics

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4409435720