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Robust Systemic and Mucosal Immune Responses to Coxsackievirus B3 Elicited by Spider Silk Protein Based Nanovaccines via Subcutaneous Immunization (Adv. Funct. Mater. 15/2025)

Year: 2025

Type: article

Abstract: Spider Silk Protein-Based Nanovaccines In article number 2407568, Xingmei Qi, Sidong Xiong, Gefei Chen, and co-workers show that spider silk protein-based nanovaccines are capable of eliciting both mucosal and systemic immune responses following subcutaneous administration and demonstrate significant protective effects against Coxsackievirus B3 infection, offering a promising approach in peptide-based parenteral vaccine strategies.

Source: Advanced Functional Materials

DOI: 10.1002/adfm.202570086

Authors: Xingmei Qi, Guoqiang Wei, Yanan Li, Sidong Xiong, Gefei Chen

Institutions: Soochow University, Second Military Medical University, Changhai Hospital, Uppsala University, Karolinska Institutet

Language: English

Topic: Silk-based biomaterials and applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4409437016

FWCI:

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