Using Phylogenetic Analysis to Detect National and International Dimensions of Hepatitis C Virus 1b Transmission Clusters - China, 1989-2021.
Year: 2025
Type: article
Abstract: What is already known about this topic?: Phylogenetic analysis has revolutionized the detection and understanding of Hepatitis C Virus (HCV) transmission patterns. What is added by this report?: Three distinct transmission cluster patterns were identified across China: a large cluster with nationwide distribution, two medium clusters predominantly in the Central and Eastern China, and 103 small clusters scattered across 19 provincial-level administrative divisions (PLADs). Each cluster type exhibited unique characteristics of expansion risk and inter-provincial transmission patterns. No genetic linkages were found between Chinese sequences and those from other countries. What are the implications for public health practice?: These findings underscore the critical need for a comprehensive national molecular epidemiological surveillance network.
Source: PubMed
Institution: Guangxi Center for Disease Prevention and Control
Language: English
Topic: Hepatitis C virus research
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4409445005