Work

Multicentric basal cell tumors in a cat

Year: 1986
Type: article
Study design: Case Report
Abstract: An adult 3.4-kg spayed female domestic longhair cat was referred to the Veterinary Medical Teaching Hospital, University of Florida, with a 1-year history of a nonhealing wound on the right hind foot.The lesion had been surgically debrided and the cat had been treated with penicillin, without improvement.The only abnormalities found on physical ex amination of the cat were 4 cutaneous lesions.One lesion was 2 cm by 2 cm, ulcerated, slightly raised, and located over the dorsum of the second and third right metatarsal bones (Fig 1).A second ulcerated, slightly raised lesion, 2 cm by 1 cm, was located over the dorsum of the second, third, and fourth right metatarsal bones.A firm, flesh-colored, 1.5 cm by 1 cm pedunculated mass was in the skin of the right inguinal region.A 0.5-cm diameter mass was freely moveable under the skin of the right tibiotarsal area.The skin surrounding the middle phalanx was erythematous and the associated pad was ulcerated.A serosanguineous discharge exuded from the ulce rated lesions.Mobility of the cat was not affected by the lesions.Radiography of the right metatarsal region revealed no evidence of bone involvement.The cat had normochromic, normocyctic anemia (pcv, 26%) and high total plasma protein concentra tion (8.4 g/dl).The anemia and hypergammaglobu linemia (5.9 g/dl) were attributed to chronic inflam mation.The cat was FeLV-negative.Bacterial culture of a biopsy specimen from one of the lesions yielded hemolytic Staphylococcus aureus, which was susceptible to all antibiotics tested.Treat ment with amoxicillin (22 mg/kg of body weight, twice daily) was begun.Biopsy of the 2 metatarsal and inguinal lesions revealed multiple basal cell tumors.The masses were removed surgically.At 3 months after surgery, the cat had no palpable evidence of recurrence of the tumors.Microscopically, all 4 masses were composed of neoplastic basaloid epithelial cells, with varying histologic patterns.The neoplastic cells in the 2 metatarsal and inguinal lesions were arranged in large, tortuous, deeply penetrating lobules, with frequent central necrosis.The inguinal neoplasm
Language: English
Field: Medicine
Open Access status: bronze
OpenAlex ID: W4409447718
FWCI:
Cites: 3
Cited by: 9
Related to: 10