Work

Selectively targeting BCL6 using a small-molecule inhibitor is a potential therapeutic strategy for glioblastoma

Year: 2025

Type: article

Abstract: and prolonged the survival of mice with tumors. In summary, our findings reveal that BCL6 appears to play a crucial role in GBM and may be a therapeutic target for treating this incurable condition.

Source: Genes & Diseases

DOI: 10.1016/j.gendis.2025.101644

Authors: Min Wu, Lin Zhang, Weikai Guo, Shiyi Lv, Wangrui Jin, Shuangshuang Zhu, Huang Chen, Shuyi Jian, Layang Liu, Yajing Xing, Shihong Peng, Mingyao Liu, Yihua Chen, Zhengfang Yi

Institutions: East China Normal University, Kunming Medical University, Shanghai Changning Maternity and Infant Health Hospital

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

Funders: National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, East China Normal University, Shanghai Rising-Star Program

Awards: G2018199512, G3826578437, G4617812232, G5047628729, G6993475043

OpenAlex ID: W4409451826

FWCI:

Cites: 34

Cited by:

Related to: 10