Work

Dual lateral flow assay using quantum nanobeads for quantitative detection of BDNF and TNF-α in tears

Year: 2025

Type: article

Abstract: for BDNF. The LFA also demonstrated superior selectivity, reproducibility, and stability to the standard enzyme-linked immunosorbent assay (ELISA). Using a 3D-printed readout box, the analysis of the LFA requires only a readily accessible smartphone and image processing software, making it an ideal POC detection tool. This ultrasensitive, economical, and user-friendly LFA demonstrates significant potential as an alternative for glaucoma screening.

Source: Lab on a Chip

DOI: 10.1039/d4lc01045k

Authors: Yue Wu, Yubing Hu, Nan Jiang, Maria W. Georgi, Ali K. Yetisen, M. Francesca Cordeiro

Institutions: Imperial College London, Sichuan University, West China Medical Center of Sichuan University, University College London

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Natural Science Foundation of China, Engineering and Physical Sciences Research Council