Year: 2025
Type: article
Study design: Case Report
Abstract: Gout is a common metabolic disorder caused by hyperuricemia, which results in the deposition of monosodium urate crystals in various parts of the body. In the present case, a large gout tophus was detected based on gout disease. Although gouty tophi might occur in many locations during a long-standing gout disease, the vast majority are located in the articular tissue. An 80-year-old female patient was admitted to the emergency room complaining of persistent nausea and vomiting for two days. In addition, she reported abdominal pain and cramps that she had not experienced before. A CT scan revealed a large calcified mesenteric mass in the right side of the abdomen. The patient underwent surgery and removal of the mesenteric mass including 55-cm jejunal resection. Histologically, sections showed a capsule-like boundary of varying widths, mostly cell-poor lesions, as well as siderophages and strong lymphatic infiltrate at the margins, corresponding to residual lymph node tissue. In the periphery of the lesion, brace-shaped dystrophic calcifications completed the histological image of a gouty tophus. In this case report, we describe an extremely rare case of a mass in the area of the small intestine mesentery caused by monosodium urate crystals. Even if patients do not present with articular manifestation of gout, deposition in other tissues is possible and presents a risk factor for the development of diseases. For patients with unclear abdominal masses suffering from hyperuricemia, despite being rare, a gout tophus should be thought of.
Source: Cureus
DOI: 10.7759/cureus.82288
Authors: Vanessa Diller, Daniel Perez, Alexander Harms, Luca M Tavernar, Sven Petersen
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409459257