Effect of Temperature on Physicochemical Properties of Plasticized Hydroxypropyl Methylcellulose K100–Carbopol 934 Films Containing Propylene Glycol as Plasticizer
Year: 2025
Type: article
Abstract: This paper studies the effect of different temperatures on different important physicochemical characteristics of plasti-cized hydroxypropyl methylcellulose (HPMC) K100-Carbopol 934 films containing propylene glycol (as a plasticizer), such as the rheology, thickness, folding endurance, tensile strength, elongation, and in vitro swelling with diffusion ki-netics. Rheology of HPMC K100-Carbopol 934 blend dispersions containing propylene glycol (before film casting) demonstrates that the flow is shear thinning and pseudoplastic. In the study of in vitro swelling, the relaxation-controlled transport is the predominant process of solvent diffusion into these plasticized HPMC K100–Carbopol 934 blend films under study. The results suggest that the solvent transport process followed second-order kinetics, and the diffusion mechanism is non-Fickian diffusion. Regular measurements of mass variation, as well as the isothermal ki-netic curves, are plotted. The plasticized HPMC K100–Carbopol 934 blend films are characterized by differential scanning calorimetry and scanning electron microscopy.
Source: Makara Journal of Science
Authors: Panda, Braja Bihari, Sahoo, Rudra Narayan, Nayak, Amit Kumar
Institution: Siksha O Anusandhan University
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4409464134