Year: 2025
Type: article
Abstract: Because of the limited efficacy of conventional therapies, Hepatocellular carcinoma (HCC) is a global health concern. A new therapeutic strategy, chimeric antigen receptor T-cells (CAR-T), has demonstrated considerable potential in treating HCC. This paper reviews the structure and mechanism and clinical application of CAR-T cells to treat HCC, with a particular focus on experimental research targeting different antigens and the combination of CAR-T CAR-T and other therapies.
Source: Biomedical Data Science
Author: Dingyi Liu
Institution: Zhejiang Chinese Medical University
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409465490