Work

Vitamin D Levels and Their Association With Periodontitis in Women With Polycystic Ovary Syndrome: A Cross-sectional Study

Year: 2025

Type: article

Abstract: Background and aim Remarkable evidence supports the hypothesis that vitamin D influences and prevents the sequelae of periodontal disease. Its deficiency has also been found among patients with polycystic ovary syndrome (PCOS), and it could be attributed to the polymorphisms in the vitamin D receptor (VDR) gene. Hence, the goal of this study is to assess the periodontal health of PCOS participants and investigate the serum vitamin D levels in patients with PCOS and periodontitis. Methods and material A cross-sectional study was conducted on 100 female participants between the ages of 18 to 40 years and were equally divided into four groups: Group 1: participants with periodontitis only; Group 2: participants with PCOS only; Group 3: participants with periodontitis and PCOS; and Group 4: participants without periodontitis and PCOS. Results Serum vitamin D levels in Group 1 (35.40±3.862), Group 2 (31.20±5.888), Group 3 (32.12±3.811), and Group 4 (33.24±5.885) presented no statistically significant differences among the groups. Many people in all study groups had lower levels of serum vitamin D. In PCOS individuals, there is no discernible decline in periodontal health. Conclusions In this study, it was concluded that serum vitamin D levels do not significantly correlate with the prevalence of PCOS or periodontitis.

Source: Cureus

DOI: 10.7759/cureus.82268