Work

MXene-based functional nanomaterials and their applications in cancer diagnosis and therapy

Year: 2025

Type: article

Abstract: MXenes are a class of novel two-dimensional nanomaterials that stand out in cancer therapy due to their high remarkable conductivity, specific surface area, strong near-infrared absorption, and preferable biocompatibility. These properties offer significant advantages in cancer therapy. Particularly when surface-modified or functionalized, MXenes demonstrate enhanced targeting capabilities and stronger cytotoxic effects on tumor tissues, showing great potential for non-invasive cancer treatment. Additionally, functional MXenes exhibit unique optical and electrical properties, offering significant potential for biological imaging and biosensing applications. This review provides a comprehensive overview of various strategies for the surface modification and functionalization of MXenes and summarizes the latest advancements in multifunctional cancer treatment platforms based on functional MXenes, covering early cancer diagnosis and various therapeutic approaches. Furthermore, this review highlights the advantages and challenges associated with the use of functional MXenes in cancer therapy and offers insights into their potential future development.

Source: Precision medicine and engineering.

DOI: 10.1016/j.preme.2025.100029

Authors: Shuoshun Li, Ziyi Xu, Rong Meng, Enhuai Wen, Qiang Peng

Institutions: Sichuan University, State Key Laboratory of Oral Diseases

Language: English

Topic: MXene and MAX Phase Materials

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,200