Year: 2025
Type: article
Study design: Case Report
Abstract: BACKGROUND: There have been no reported cases of infectious diseases associated with Clonostachys rosea. CASE PRESENTATION: The patient, 53 years old, was admitted with complaints of "foreign body sensation, tearing, and pain in the left eye for 2 weeks, aggravated for 7 days". And was admitted with a diagnosis of "fungal keratitis (left)". Fungal growth was confirmed through corneal scrape culture. Antifungal treatment included natamycin and fluconazole eye drops, along with oral terbinafine tablets. Levofloxacin eye drops were administered to prevent bacterial infection, and praprofen eye drops were prescribed to alleviate anterior chamber reaction. After 4 days of treatment, the patient reported reduced foreign body sensation, tearing, and pain in the left eye. Follow-up visits were scheduled at regular intervals, during which medication remained consistent and dosage gradually decreased with symptom improvement. After 35 days, ulcer lesions had formed scars, and confocal examination of the corneal focal area revealed normal epithelial cell growth with scar-like reflection below, without obvious mycelial hyperrefraction. CONCLUSIONS: Herein, we describe a case of corneal infection attributed to Clonostachys rosea. We outline the development and treatment of this infection to enhance clinical comprehension and management of similar cases.
Source: BMC Infectious Diseases
Authors: Xiaona Liu, Juanjuan Zheng, Zihan Huo, Feng Wu
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,090
OpenAlex ID: W4409504063