Predictive factors for postoperative outcome after endolymphatic sac surgery. Part 1: Clinical and prognostic STROBE report
Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: To evaluate preoperative predictive factors 2years after endolymphatic sac surgery (ESS) in patients with Ménière's disease (MD). MATERIALS AND METHODS: A retrospective single-center study included patients who underwent ESS between 2015 and 2022, with unilateral MD according to the criteria of the American Academy of Otolaryngology - Head and Neck Surgery (AAO-HNS) as revised in 2015, and resistant to first-line medical treatment. The main study endpoint was the incidence of postoperative vertigo episodes. Secondary endpoints comprised hearing preservation at 2years and surgical efficacy. RESULTS: Thirty-eight patients were included. Significant vertigo control was achieved in 63% (n=24). No predictive factors were identified for vertigo control or improvement in quality of life. Pure-tone and speech audiometric results were preserved at 2years. Whether the endolymphatic sac was sectioned or not did not significantly impact surgical outcome. CONCLUSION: No predictive factors for successful ESS emerged. ESS is a conservative second-line surgical treatment, with key indications for bilateral MD or MD in patients with preserved hearing.
Institution: Centre Hospitalier Universitaire de Nantes
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,700
OpenAlex ID: W4409507079
