Comparison of Visual Outcome of Successful Descemet Membrane Endothelial Keratoplasty and Penetrating Keratoplasty
Year: 2025
Type: article
Abstract: OBJECTIVE: To compare the visual outcome in patients undergoing penetrating keratoplasty (PKP) with descemet membrane endothelial keratoplasty (DMEK). STUDY DESIGN: A quasi-experimental study. Place and Duration of the Study: Department of Eye, The Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan, from January 2022 to June 2023. METHODOLOGY: A prospective analysis of fourteen patients who underwent PKP in comparison with another group of fourteen patients who got the DMEK surgery was done. The evaluation of visual and refractive outcomes was done postoperatively. Fisher's exact test was used to compare visual acuity grouped into categories between two surgical procedures. RESULTS: Fourteen eyes from each group that were PKP and DMEK were included in the analysis. The best corrected visual acuity after 6 months was better in the DMEK group compared with the PKP group (p = 0.003) and these results were consistent after twelve months (p = 0.006) keeping the DMEK group superior in visual outcome over the PKP group. CONCLUSION: PKP and DMEK play distinct roles in the treatment of corneal disorders, each with its own set of indications. However, DMEK resulted in a better visual outcome when compared to the PKP. Although quality of life improved in both groups, it was found to be better in the DMEK group compared to the PKP group. KEY WORDS: Visual acuity, Descemet membrane endothelial keratoplasty, Penetrating keratoplasty, Corneal transplant.
Authors: Teyyeb Azeem Janjua, Anam Hassan, Waqar Muzaffar, Shagufta Parveen, Muhammad Shahid, Jawwad Ahmad
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409512543