Phytochemical Screening and Gc-Ms Profile of Melastomastrum Capitatum A. and R. Fern. Methanol Root Extract for Bioactive Anti-Brain Tumor Compounds
Year: 2025
Type: article
Abstract: Melastomastrum capitatum is a tropical fruit tree of considerable economic importance, originating from West and tropical Africa.Belonging to the Melastomataceae family, M. capitatum has been traditionally used to address ailments such as cancer, stomachache, diabetes, pain, and inflammation.The current study aimed to analyze the phytochemical constituents of the methanol extract from the root of M. capitatum using phytochemical assessment and gas chromatography-mass spectrometry (GC-MS).The phytochemical analysis revealed seven compounds, including alkaloids, saponins, flavonoids, steroids, cardiac glycosides, and terpenoids, with saponins being the most abundant at 51.8%.The GC-MS analysis detected many bioactive compounds that such as phthalic acid derived compounds and others which may contribute to various pharmacological effects.Linoleic acid was the most prevalent compound found, known for its antioxidant, antiinflammatory, and antidiabetic properties.Phthalic acid derivatives were also noted for their antimicrobial, anticancer, antioxidant, and anti-inflammatory effects.Additionally, other noteworthy compounds such as 3,4-Dihydroxyphenylglycol (4TMS derivative) and 2,4-Pentadien-1-ol, 3-propyl-were identified, recognized for their antioxidant and anticancer capabilities, respectively.These results lend support to the traditional use of M. capitatum for treating various health issues.
Institutions: University of Maiduguri, Ahmadu Bello University
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
Funder: Tertiary Education Trust Fund
OpenAlex ID: W4409513625