Work

Cycloaddition reaction of NaN 3 with nitriles toward the synthesis of tetrazoles catalyzed by a copper complex on boehmite nanoparticles

Year: 2025

Type: article

Abstract: In the present study, the synthesis of boehmite nanoparticles was done using a hydrothermal method using an aluminum source in water solvent. The synthesized boehmite support was modified using (3-iodopropyl)trimethoxysilane (3-IPTMS), and then the modified boehmite was functionalized using a Schiff-base ligand. Finally, copper ions were immobilized on the functionalized boehmite denoted as a boehmite@Schiff-base-Cu nanocatalyst. The synthesized catalyst was identified and confirmed using SEM, FT-IR, TGA, EDXS, WDX, XRD, and BET techniques. The activity of boehmite@Schiff-base-Cu was investigated in preparing 5-substituted tetrazoles using nitrile derivatives and sodium azide, in which short reaction times and high yields were observed in described reactions. Also, the many advantages of the boehmite@Schiff-base-Cu nanocatalyst are ease of operation, compatibility with the environment, its easy separation from the reaction medium, and the ability to reuse it several times without significantly reducing its catalytic activity.

Source: Nanoscale Advances

DOI: 10.1039/d5na00081e

Authors: Arida Jabbari, Bahman Tahmasbi, Elham Mohseni, Mitra Darabi

Institutions: Islamic Azad University, Tehran, Ilam University

Language: English

Topic: Synthesis of Tetrazole Derivatives

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,962

Funders: Islamic Azad University, Ahar Branch, Islamic Azad University, Ilam University