Year: 2025
Type: article
Abstract: The prevalence of alcohol use disorder (AUD) and alcohol-related liver disease (ALD) has increased in the last two decades. ALD is currently the most common indication for both waitlist additions and liver transplant (LT) in the United States, including alcohol-associated cirrhosis, alcohol-associated hepatitis (AH), and acute-on-chronic liver failure (ACLF). ALD also has a significant global disease burden. LT in ALD is a complex paradigm that poses both medical and ethical challenges, requiring a multidisciplinary approach to management. Furthermore, the scope of liver transplantation for alcohol use is expanding. Here we review updates in LT for ALD pertinent for the practicing clinician. We will discuss current practice patterns, treatment strategies, and outcomes.
Source: OBM Transplantation
Authors: Michael J Eiswerth, Joel Wedd
Institution: Virginia Commonwealth University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409519111