Work

Ultrasound Neuromodulation (Low‐Intensity Focused Ultrasound) to Treat Knee Osteoarthritis Pain

Year: 2025

Type: article

Abstract: Low-intensity focused ultrasound is a non-invasive neuromodulation technique that delivers mechanical forces to a deep location within the body through acoustic pressure waves without affecting tissue between the transducer and focal target. Preliminary studies involving healthy volunteers suggest focused ultrasound reversibly prevents action potential formation similar to a local anesthetic nerve block, but the modality has not been used in patients with existing pain. The current randomized pilot study was undertaken to 1) determine the feasibility and optimize the protocol for a subsequent definitive clinical trial; and 2) monitor for related complications of focused ultrasound when treating knee osteoarthritis pain.

Source: Journal of Ultrasound in Medicine

DOI: 10.1002/jum.16706

Authors: Brian M. Ilfeld, Khoa N. Cao, Ruben Branson, Philip Bloom

Institutions: Cleveland Clinic, University of California San Diego, Monash University

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,100