Evaluation of the Efficacy of Intravenous Infusion of 1000 mg Paracetamol as Intrapartum Labor Analgesia
Year: 2025
Type: article
Abstract: A BSTRACT Background: It is vital to assess methods of reducing the most severe labor pain. Paracetamol infusion is an efficient therapy available to eliminate labor pain in the active phase. Aim: The present study aimed to assess the efficacy of intravenous infusion of 1000 mg paracetamol as an intrapartum labor analgesic. Methods: In 220 nulliparous pregnant females undergoing vaginal delivery, after active labor phase onset, subjects were divided into two groups. Group I subjects were given 300cc normal saline and Group II subjects were given 300cc normal saline and 1 gram paracetamol. In two groups, Apgar scores, delivery type, duration of first and second labor stages, VAS scores, and maternal pain scores were assessed and compared. Results: Mean first- and second-stage labor length was significantly lower in Group I compared to Group II with P = 0.001 and 0.037. Also, mean pain scores were significantly lower in paracetamol Group II compared to a control group with P < 0.05. Conclusions: Intravenous paracetamol prescription not only reduces labor pain in pregnant females but also decreases the duration of different labor stages, reduces the need for cesarean birth, and increases patient satisfaction with natural childbirth.
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $250
OpenAlex ID: W4409522012