Year: 2025
Type: article
Abstract: reduced nanoparticles for Raman signal enhancement of sweat components. The design of the patch avoids the direct exposure of nanoparticles and the excitation laser to the skin. The volume ratio of polydimethylsiloxane to oleic acid in the adhesive mixture was optimized for maximum adhesion to various substrates with oil residue. The plasmonic paper employed here exhibited excellent limits of detection of 55.9 μM and 47.8 μM for the sweat components urea and lactate, respectively. By utilizing the skin-adhesive patch, the multiplexed detection of urea and lactate could be achieved directly from sweat using surface-enhanced Raman spectroscopy. The developed SERS patch can be potentially utilized as a wearable healthcare sensor for the molecular fingerprinting of body fluids and opens avenues for the development of such sensors in the field of wearable personalized healthcare devices.
Source: RSC Advances
DOI: 10.1039/d5ra00529a
Institution: Manipal Academy of Higher Education
Language: English
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,042
OpenAlex ID: W4409522516
