Genetic diversity of Plasmodium falciparum in people living with HIV in Ogbomoso, Nigeria: Implications for malaria transmission and treatment
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: among PLWH in Ogbomoso, Nigeria. Materials and Methods: genes was performed to assess genetic diversity. The distribution of allelic families was analysed descriptively using SPSS v.27, and a p-value≤ 0.05 was considered statistically significant. Results: samples were predominantly monoclonal (22.1%). . Conclusions: isolates from PLWH exhibited relatively low genetic diversity, suggesting a potential reduction in malaria transmission and signalling the effectiveness of malaria control strategies. Further studies are needed to explore the underlying factors leading to reduced transmission and low genetic variations in this population and their potential impact on malaria transmission and treatment outcomes in PLWH.
Source: PubMed
Authors: Odesola, Damilola E., Mbabie, Ure C., Makinde, Oreoluwa H., Olaosebikan, Iyanuoluwa O., James, Ogunniran A., Ayoola, Adeola O., Opaleye, Oluyinka O., Ojurongbe, Olusola
Institutions: Ladoke Akintola University of Technology, Duke University
Language: English
Topic: Malaria Research and Control
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Alexander von Humboldt-Stiftung
OpenAlex ID: W4409525617