Work

Local Versus Systemic Cytokine Dynamics in Pediatric Pneumonia

Year: 2025

Type: article

Study design: Observational Study

Abstract: No significant correlation was observed between most local and systemic cytokines in children with pneumonia. The observed elevation of specific cytokines such as IL-2, IL-2R, and IL-4 in the BALF of pneumonia patients, alongside increases in IL-2, IL-6, and IL-12p70 in peripheral blood, underscores the robust local and systemic inflammatory response in pneumonia.

Source: Pediatric Pulmonology

DOI: 10.1002/ppul.71093

Authors: Jilei Lin, Mingyu Tang, Shuhua Yuan, Jiande Chen, Guijun Yang, Huishan Zhang, Wanlin Li, Jing Zhang, Lei Zhang, Yong Yin

Institutions: Shanghai Jiao Tong University, Shanghai Children's Medical Center, Sanya City Women and Children Hospital

Language: English

Topic: Pneumonia and Respiratory Infections

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Shanghai Municipal Health Commission, Shanghai Jiao Tong University

OpenAlex ID: W4409527229

FWCI: 1.219

Cites: 7

Cited by: 2

Related to: 10