Cover Feature: The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit to Lead (ChemMedChem 8/2025)
Year: 2025
Type: article
Abstract: “Searching for diamonds in the rough” summarises consensus best practices in how to expedite the processes and enable decision making in the Hits-to-Leads phase of drug discovery. The EFMC Best Practices Group, led by Jean Quancard, draws on expertise from seasoned drug hunters (industrial and academic) from all over Europe, producing open-source educational materials. This paper complements webinars on the topic, part of an expanding series with associated online content (videos of presentations, slides, publications) produced to be open-source educational materials. More details can be found in article 10.1002/cmdc.202400931 by Jean Quancard, Robert J. Young, and co-workers.
Source: ChemMedChem
Institutions: Novartis (Switzerland), University of Copenhagen, University of Milan, Boehringer Ingelheim (Germany), AstraZeneca (Sweden), Merck KGaA, Darmstadt (Germany), Merck Healthcare KGaA, Darmstadt (Germany), University of Tübingen, Johnson & Johnson (United States), Orion Corporation (Finland), University of Salerno, University of Sussex
Language: English
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4409538752