A multimodal opioid‐sparing anaesthetic approach in a cat forelimb amputation, utilising perioperative magnesium sulphate administration
Year: 2025
Type: article
Study design: Case Report
Abstract: An 8‐year‐old, male, neutered cat underwent forelimb amputation to manage a fibrosarcoma. Utilising a multimodal opioid‐sparing approach, dexmedetomidine, midazolam and buprenorphine were administered for premedication, while induction and maintenance of anaesthesia were achieved with propofol. Additionally, a constant rate of infusion of ketamine and magnesium sulphate, regional ropivacaine infusion through a wound infusion catheter, meloxicam and pregabalin were administered throughout the perioperative period. Postoperative pain was assessed with Unesp–Botucatu Feline Pain Scale and Feline Grimace Scale, while serial measurements of serum magnesium concentrations were carried out up to 36 hours postoperatively. No rescue analgesia was required during the intraoperative or postoperative period, and the cat was discharged on the fourth postoperative day. After 18 months, the cat remains asymptomatic without signs of cancer recurrence. This opioid‐sparing approach contributed to intraoperative haemodynamic stability and an optimal analgesic outcome, despite minimum opioid utilisation. Furthermore, no serious adverse effects, related to magnesium perioperative administration, were observed.
Source: Veterinary Record Case Reports
DOI: 10.1002/vrc2.70036
Institutions: WEK Tierarzt, University of Thessaly
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4409554512