Network Meta-Analysis of Different Traditional Chinese Medicine External Treatments for Bronchial Asthma
Year: 2025
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: 目的：运用网状Meta分析方法比较不同中医外治疗法治疗支气管哮喘的临床疗效，为临床治疗方案的选择提供循证依据。方法：计算机检索PubMed、Embase、The Cochrane Library、Web of Science、中国知网(CNKI)、万方数据知识服务平台(WF)、维普(VIP)、中国生物医学数据库(CBM)八大数据库自建库以来关于6种中医外治疗法治疗支气管哮喘的随机对照试验(Randomized Controlled Trial, RCTs)。由两名研究员进行文献筛查和数据提取，采用RevMan 5.3软件和Stata 15.0软件进行文献质量评价、网状Meta分析。结果：共纳入61项RCTs。网状Meta分析结果显示，各干预措施对总有效率的曲线下面积(SUCRA)排序结果显示：穴位贴敷(80.5%) > 推拿(70.8%) > 电针(60.6%) > 灸法(55.3%) > 温针灸(48.7%) > 针刺(29.1%) > 西药(4.9%)。各干预措施对FVC的SUCRA排序结果显示：穴位贴敷(80.4%) > 针刺(72.0%) > 电针(53.3%) > 灸法(32.9%) > 西药(11.4%)。各干预措施对症候积分的SUCRA排序结果显示：穴位贴敷(89.9%) > 灸法(83.4%) > 针刺(51.8%) > 电针(15.9%) > 西药(9.1%)。结论：在7种干预措施中，综合总有效率、FVC、症候积分相关结局指标的排序，穴位贴敷疗法是治疗支气管哮喘的最佳选择。但因现有研究质量的限制，日后仍需更多高质量的RCTs去证实这个结论。Objective: To compare the clinical efficacy of different acupuncture therapies in the treatment of bronchial asthma by network meta-analysis and to provide an evidence-based basis for the selection of clinical treatment options. Methods: The randomized controlled trials (RCTs) of 6 kinds of acupuncture and moxibustion therapy for bronchial asthma were searched in PubMed, Embase, The Cochrane Library, Web of Science, CNKI, WF, VIP, and CBM databases since the establishment of the database. Two researchers performed literature screening and data extraction. RevMan 5.3 software and Stata 15.0 software were used for literature quality evaluation and network meta-analysis. Results: A total of 61 RCTs were included. The results of the network meta-analysis showed that the SUCRA ranking results of the total effective rate of each intervention showed that acupoint application (80.5%) > massage (70.8%) > electroacupuncture (60.6%) > moxibustion (55.3%) > warm acupuncture (48.7%) > acupuncture (29.1%) > western medicine (4.9 %). The SUCRA ranking results of each intervention on FVC showed that acupoint application (80.4%) > acupuncture (72.0%) > electroacupuncture (53.3%) > moxibustion (32.9%)> western medicine (11.4%). The SUCRA ranking results of the intervention measures on symptom scores showed that acupoint application (89.9%) > moxibustion (83.4%) > acupuncture (51.8%) > electroacupuncture (15.9%) > western medicine (9.1%). Conclusion: Among the seven interventions, comprehensive total effective rate, FVC, symptom score-related outcome indicators, and acupoint application therapy are the best choices for the treatment of bronchial asthma. However, due to the limitation of the quality of existing studies, more high-quality RCTs are needed to confirm this conclusion in the future.
Source: Traditional Chinese Medicine
Author: 燕平 刘
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4409565616